• J. Int. Med. Res. · May 2010

    Case Reports

    Malignant atrophic papulosis with severe gastrointestinal perforation and omental necrosis: a case report.

    • X Y Zheng, D Y Huang, Y Xin, and X F Wang.
    • Department of General Surgery, Affiliated Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
    • J. Int. Med. Res. 2010 May 1; 38 (3): 1164-9.

    AbstractMalignant atrophic papulosis (MAP) is a rare disease with an extremely grim prognosis, death being due to gastrointestinal perforation and neurological disorders. We report a severe case of MAP in a 37-year old woman. The patient had three emergent laparotomies in 3 months for recurrent acute peritonitis due to omental thrombosis resulting in necrosis, multiple intestinal and mesenteric lesions, and severe gastrointestinal perforations. Multiple papular skin lesions were present for 1 year prior to surgery. Pathological findings revealed MAP. Surgical intervention was successful and the patient recovered smoothly but later died of malnutrition and septicaemia.

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