• Thrombosis research · May 2014

    Multicenter Study

    Thromboprophylaxis use and concordance with guidelines among medical and surgical patients in Morocco.

    • Tazi Mezalek Zoubida, Abderahim Azzouzi, Wafaa Bono, Rajae Tachinante, Mamoun Faroudy, Lamiaa Essaadouni, and Chakib Nejjari.
    • Internal Medicine Department, Ibn Sina University Hospital, Rabat, Morocco. Electronic address: z.tazimezalek@gmail.com.
    • Thromb. Res. 2014 May 1; 133 (5): 725-8.

    IntroductionNo data are available on thromboprophylaxis use in Morocco. Our aim was to characterize patients at risk of venous thromboembolism and assess the rate of appropriate thromboprophylaxis.Materials And MethodsThis was a national, observational, multicentre survey of venous thromboembolism risk and thromboprophylaxis use in hospitalized patients. Data were collected on a predefined date in three university hospitals in Morocco using a standardized pre-printed form. Thromboembolic risk was assessed according to the American College of Chest Physicians (ACCP) 2008 guidelines. Patients were classified as "thromboprophylaxis indicated" or "thromboprophylaxis not indicated".Results784 patients were analysed: 307 (39.2%) medical and 477 (60.8%) surgical. 421 (53.7%) were female. Medical patients were older than surgical patients (57.6 ± 11.5 vs. 46.2 ± 16.9 years, p<0.0001) and were more likely to have risk factors for thromboembolism (50.5% vs. 45.7% of patients, p=NS). 57% of patients without contraindications or bleeding risk were at risk of thromboembolism according to ACCP guidelines and thromboprophylaxis was prescribed to 42.8% of these patients. In contrast, 7.4% of patients with no thromboembolic risk also received thromboprophylaxis (proportion agreement: 61.0%; Kappa=0.296). Over half (54.5%) of medical patients at risk of thromboembolism did not receive thromboprophylaxis whereas 6.3% of those with no risk did receive it (proportion agreement: 76.4%; Kappa=0.433). These figures were 57.9% and 9.2%, respectively, for surgical patients (proportion agreement: 52.7%; Kappa=0.191). Thromboprophylaxis was given to 19.2% of patients with contraindications or a bleeding risk.ConclusionsEducational initiatives are imperative to inform doctors about appropriate thromboprophylaxis.Copyright © 2014 Elsevier Ltd. All rights reserved.

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