• A & A case reports · Mar 2017

    Case Reports

    Suspected Malignant Hyperthermia in the Setting of Hypothermic Circulatory Arrest for Type A Aortic Dissection Repair: A Case Report.

    • Bryant Bunting, Joshua Knight, and Stephen M McHugh.
    • From the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
    • A A Case Rep. 2017 Mar 1; 8 (5): 116-118.

    AbstractMalignant Hyperthermia (MH) is a life-threatening biochemical process of hypermetabolism brought about in susceptible individuals by a triggering drug or event. Type A aortic dissections are surgical emergencies requiring cardiopulmonary bypass and frequently deep hypothermic circulatory arrest. We present a case of suspected MH in a patient undergoing emergent repair of a type A aortic dissection. Upon arrival at our institution, the patient had multiple signs of MH. However, no known triggering agent had been administered. Eventually, the unique physiologic changes of cardiopulmonary bypass provided strong support for the diagnosis of MH and dantrolene was administered, effectively treating the episode.

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