• Hui Luo, Yanling Chen, Yian Zhang, Yufei Wang, Hualan Deng, and Dejiao Yao.
• Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu.
• Medicine (Baltimore). 2021 May 28; 100 (21): e26014e26014.

BackgroundRadiation enteritis (RE) is a common complication that often occurs after radiotherapy for abdominal and pelvic malignancies. RE could influence patients' quality of life seriously and it is difficult to cure by conventional treatments. A lot of studies have revealed that the external treatment of traditional Chinese medicine (TCM) for RE is a safe and economical approach, but there is no relevant systematic review. The present study performed a systematic review and meta-analysis to compare TCM external treatment and conventional treatment for RE to evaluate the effectiveness and safety of external treatment of traditional Chinese medicine in the treatment of RE.MethodsCochrane Library, PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wan-Fang database, VIP Chinese Science and Technique Journals Database, and the Chinese Biomedical Literature Database (CBM) were searched. The time of publication was limited from inception to April, 2021. Two reviewers independently searched for the selected articles and extract the data. The RevMan V.5.3 statistical software (Cochrane Collaboration) and Stata V.16.0 software were used to conduct the meta-analysis.ResultsWe will show the results of this study in a peer-reviewed journal.ConclusionThis meta-analysis will provide reliable evidence for external treatment of TCM in the treatment of RE.Inplasy Registration NumberINPLASY202140120.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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