• Clinics in chest medicine · Sep 2017

    Review

    Candidemia in the Intensive Care Unit.

    • Oleg Epelbaum and Rachel Chasan.
    • Division of Pulmonary, Critical Care, and Sleep Medicine, Westchester Medical Center, New York Medical College, 100 Woods Road, Macy Pavilion Room 1042, Valhalla, NY 10595, USA. Electronic address: oleg.epelbaum@wmchealth.org.
    • Clin. Chest Med. 2017 Sep 1; 38 (3): 493-509.

    AbstractCandidemia presents several challenges to the intensive care unit (ICU) community. Recognition and treatment of this infection is frequently delayed, with dramatic clinical deterioration and death often preceding the detection of Candida in blood cultures. Identification of individual patients at the highest risk for developing candidemia remains an imperfect science; the role of antifungal therapy before culture diagnosis is yet to be fully defined in the ICU. The absence of well-established molecular techniques for early detection of candidemia hinders efforts to reduce the heavy clinical and economic impact of this infection. Echinocandins are the recommended antifungal drug class for the treatment of ICU candidemia.Copyright © 2017 Elsevier Inc. All rights reserved.

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