• Journal of anesthesia · Apr 2012

    Case Reports

    Successful treatment of severe asthma-associated plastic bronchitis with extracorporeal membrane oxygenation.

    • Momoka Tonan, Akio Kimura, Hiroki Matsuyama, Hiromi Kinose, Maiko Sawada, Natsuko Tokuhira, Yuko Kato, Masayuki Sasaki, Kunihiko Tsuchiya, Satoshi Higaki, and Tadaki Oomae.
    • Department of Anesthesiology and Intensive Care, Kyoto Prefectural University of Medicine, 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
    • J Anesth. 2012 Apr 1;26(2):265-8.

    AbstractWe describe a case of near-fatal asthma requiring extracorporeal membrane oxygenation (ECMO). The patient presented with severe respiratory distress, which was not responsive to conventional pharmacological therapy. The patient also failed to respond to mechanical ventilation and thus was placed on venovenous ECMO for temporary pulmonary support. A fiberoptic bronchoscopy revealed that large amounts of thick bronchial secretions had occluded the main bronchus, which suggested plastic bronchitis secondary to asthma. Aggressive airway hygiene with frequent bronchoscopies and application of biphasic cuirass ventilation for facilitation of secretion clearance were performed to improve the patient's respiratory status. The patient achieved a full recovery and suffered no neurological sequelae. This case illustrates that aggressive pulmonary hygiene with ECMO is a useful therapy for patients with asthma-associated plastic bronchitis.

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