• Katsuo Usuda, Motoyasu Sagawa, Sumiko Maeda, Nozomu Motono, Makoto Tanaka, Yuichiro Machida, Takuma Matsui Munetaka Matoba, Naoto Watanabe, Hisao Tonami, Yoshimichi Ueda, and Hidetaka Uramoto.
• Department of Thoracic Surgery, Kanazawa Medical University, Ishikawa, Japan E-mail : usuda@kanazawa-med.ac.jp.
• Asian Pac. J. Cancer Prev. 2016 Jan 1; 17 (6): 2775-80.

BackgroundPrecise staging of lung cancer is usually evaluated by PET-CT and brain MRI. Recently, however, whole-body diffusion-weighted magnetic resonance imaging (WB-DWI) has be applied. The aim of this study is to determine whether the diagnostic performance of lung cancer staging by WB-DWI is superior to that of PET-CT+brain MRI.Materials And MethodsPET-CT + brain MRI and WB-DWI were used for lung cancer staging before surgery with 59 adenocarcinomas, 16 squamous cell carcinomas and 6 other carcinomas.ResultsPET-CT + brain MRI correctly identified the pathologic N staging in 67 patients (82.7%), with overstaging in 5 (6.2%) and understaging in 9 (11.1%), giving a staging accuracy of 0.827. WB-DWI correctly identified the pathologic N staging in 72 patients (88.9%), with overstaging in 1 (1.2%) and understaging in 8 patients (9.9%), giving a staging accuracy of 0.889. There were no significant differences in accuracies. PET-CT + brain MRI correctly identified the pathologic stages in 56 patients (69.1%), with overstaging in 7 (8.6%) and understaging in 18 (22.2%), giving a staging accuracy of 0.691. WB-DWI correctly identified the pathologic stages in 61 patients (75.3%), with overstaging in 4 (4.9%) and understagings in16(19.7%), giving a staging accuracy of 0.753. There were no significant difference in accuracies.ConclusionsDiagnostic efficacy of WB-DWI for lung cancer staging is equivalent to that of PET-CT + brain MRI.

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