• Adriana Cunha Vargas, Catia Dell Agnolo, Willian Augusto de Melo, Fernando Castilho Pelloso, Lander Dos Santos, Maria Dalva de Barros Carvalho, and Sandra Marisa Pelloso.
• Department of Health Sciences, Maringá State University, Maringa, Paraná, Brazil.
• Asian Pac. J. Cancer Prev. 2020 Jan 1; 21 (1): 55-62.

ObjectiveThis study aimed to analyze the trend in cervical cancer (ICD C53) mortality in Brazilian regions in women who are who are screened and not screened from 1996 to 2015.MethodsAn epidemiological study, of time series of mortality from cervical cancer performed in 90,856 women under 24 years old (343 women), between 25 and 64 years old (32,703 women), and over 65 years old (10,909 women). The data from this research were collected from the DATASUS, from the SIM Health Surveillance Secretariat files, captured through TABNET selecting the resident population by gender and age group and ICD 10 C53 from 1996 to 2015.ResultsAmong women, 43.8% were white, and 76% had less than eight years of formal education. Polynomial regression showed an increasing trend in cervical cancer mortality in Brazil for women aged 15 - 24 years (p=0.01). Between 25 - 64 and 65 years or older it remained constant, but high (p=0.07; 0.99). The Northeast region pointed a growing trend in women aged 15 to 24 (p=0.01), 25 to 64 years (p=0.01) and 65 or older (p=0.001). The Northeast presented the highest average growth per year. In the Southeast, South and Midwest regions, decreasing trends were observed despite the high rates. The Joinpoint regression showed a 95% confidence interval, and that mortality from cervical cancer in the North region increased throughout the period analyzed. an increasing trend was observed from 1996 to 1998, whereas in the Midwest region, the trend remained stable throughout the period analyzed. The Federal District presented an upward trend from 1996 to 2015. In Brazil, an upward trend was observed throughout the whole period analyzed.ConclusionsCervical cancer mortality in younger women is becoming more predominant, in addition to the high rate observed for women aged 65 or older. 
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