Olfactory gyrus intracerebral hemorrhage in a patient with

J Clin Neurosci · Sep 2020

Case Reports

Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection.

Since the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. ⋯ Given that loss of smell is considered a relatively common symptom of this pandemic, it is an intriguing association of COVID-19 and olfactory gyrus ICH for neurotropism of SARS-CoV2 for olfactory bulb and glia cells through nasal mucosa. Future studies will need to elucidate the exact mechanism of anosmia from COVID-19 and potential mechanisms leading to ICH.

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- Sai Si Thu, Nassim Matin, and Steven R Levine.
- Departments of Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Department of Neurology, Kings County Hospital Center, Brooklyn, NY, United States. Electronic address: saisi.thu@downstate.edu.
- J Clin Neurosci. 2020 Sep 1; 79: 275-276.
AbstractSince the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. The area of hemorrhage is not a common location for spontaneous hemorrhage. Given that loss of smell is considered a relatively common symptom of this pandemic, it is an intriguing association of COVID-19 and olfactory gyrus ICH for neurotropism of SARS-CoV2 for olfactory bulb and glia cells through nasal mucosa. Future studies will need to elucidate the exact mechanism of anosmia from COVID-19 and potential mechanisms leading to ICH.Copyright © 2020 Elsevier Ltd. All rights reserved.

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Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection.

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