• Internal medicine · Dec 2021

    Case Reports

    Rheumatoid Arthritis Accompanying Diffuse Panbronchiolitis.

    • Taisuke Isono, Shun Shibata, Yuma Matsui, Chiaki Hosoda, Yoshinori Kawabata, Yoshihiko Shimizu, and Noboru Takayanagi.
    • Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.
    • Intern. Med. 2021 Dec 1; 60 (23): 3779-3783.

    AbstractA 58-year-old woman with rheumatoid arthritis (RA) visited our hospital complaining of a persistent cough and sputum for the past year. She had a high cold hemagglutinin titer and chronic sinusitis. Chest computed tomography revealed bilateral diffuse centrilobular nodules, bronchiectasis, and bronchial wall thickening. A surgical lung biopsy was performed that confirmed diffuse panbronchiolitis (DPB) because of the lymphocytic and plasmacytic infiltrates in the respiratory bronchioles. Her condition improved after the administration of clarithromycin. Several cases of RA complicating DPB have previously been reported, but only in Japan. We need to consider DPB as a bronchiolitis types accompanying RA among Japanese patients.

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