• Ugeskrift for laeger · Jan 2015

    Case Reports

    [Pregabalin can cause addiction and withdrawal symptoms].

    • Julie Nordgaard and Gesche Jürgens.
    • Psykiatrisk Center Hvidovre, Brøndbyøstervej 160, 2605 Brøndby. julie.nordgaard.frederiksen@regionh.dk.
    • Ugeskr. Laeg. 2015 Jan 26; 177 (2A): 38-9.

    AbstractA 38-year-old man was referred to the psychiatric department due to auditory hallucinations, suicidal ideation and a large daily intake of 8.4 g pregabalin. The Danish National Medication Register showed that the patient had bought pregabalin 21 times within the last two months, a total of 487.2 g pregabalin. Withdrawal symptoms disappeared within 48 hours, psychotic experiences and the suicidal ideations faded during the next couple of weeks. High doses of pregabalin are tolerated with surprisingly few toxicological consequences, though lethal cases have been described. Pregabalin abuse, however, can lead to dependency.

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