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- Wen-Hua Dong, Wen-Li Mei, You-Xing Zhao, Yan-Bo Zeng, Wen-Jian Zuo, Hui Wang, Xiao-Na Li, and Hao-Fu Dai.
- Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, P. R. China.
- Planta Med. 2011 Oct 1; 77 (15): 1730-4.
AbstractBioassay-guided fractionation of the ethanolic extract from the seeds of Antiaris toxicaria led to the isolation of three new cardiac glycosides named toxicarioside J, toxicarioside K, and toxicarioside L, together with a known glucostrophalloside. The structures of the new compounds were elucidated by spectroscopic methods including HRESIMS, UV, IR, and 1D, 2D NMR techniques. The cytotoxic activities of these cardiac glycosides against human gastric (SGC-7901) and human hepatoma (SMMC-7721) cell lines were evaluated, and all of them exhibited significant cytotoxicity.© Georg Thieme Verlag KG Stuttgart · New York.
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