• Joana Nicolau, Luisa Ayala, Aina Bonet, Bárbara Manga, Josep María Muñoz, Joseba Olea, and Apolonia Gil.
• Servicio de Endocrinología y Nutrición, Clínica Rotger , Palma, Islas Baleares, España; Servicio de Endocrinología y Nutrición, Hospital Universitario Son Llàtzer, Palma, Islas Baleares, España; Instituto de Investigación de Baleares (IdISBa), Palma, Islas Baleares, España. Electronic address: jnicolauramis@gmail.com.
• Med Clin (Barc). 2022 Feb 11; 158 (3): 105-110.

Background And ObjectivesOne of the potential negative effects of a lockdown are changes in dietary and lifestyle patterns, which can lead to weight gain. Our objective was to assess the changes on dietary habits and eating patterns in a lockdown situation and their impact on weight. We aimed to determine whether the treatment with GLP1 analogues (aGLP1) could impact on these parameters.Material And Methods100 overweight/obese patients were consecutively recruited for a review at the end of the lockdown. A structured interview was designed to see changes in dietary habits, routines and exercise.Results52% patients gained weight during lockdown. The percentage of subjects with an active history of depression or anxiety was higher among the group of patients who gained weight. The percentage of patients who worsened their hyperphagia was higher in those who gained weight (71.2% vs. 10.6%; P<0.0001); similar results were observed with binge eating (92% vs. 10.6%; p<0.0001) and cravings, both sweet and salty (69.2% vs. 21.3% and 69.2% vs. 14.9%; p<0.0001 and p<0.0001 respectively). Of the 48 patients who did not gain weight, 30 were under aGLP1 treatment (61.7%). The worsening of abnormal eating patterns was lower among patients treated with aGLP-1.ConclusionsA lockdown is a vulnerable period to gain weight, especially in those patients with a psychopathological history. aGLP1 manage to control emotional eating, making them a valuable therapeutic option.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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