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Wien. Klin. Wochenschr. · May 2019
Review[Diagnosis and management of patients with diabetes and co-existing osteoporosis (Update 2019) : Common guideline of the Autrian Society for Bone and Mineral Research and the Austrian Diabetes Society].
- Christian Muschitz, Alexandra Kautzky-Willer, Martina Rauner, Yvonne Winhöfer-Stöckl, and Judith Haschka.
- Externe Lehre, Medizinische Universität Wien, Wien, Österreich. christian.muschitz@meduniwien.ac.at.
- Wien. Klin. Wochenschr. 2019 May 1; 131 (Suppl 1): 174-185.
AbstractFragility fractures are increasingly recognized as a complication of both type 1 and type 2 diabetes, with fracture risk that increases with disease duration and poor glycemic control. The identification and management of fracture risk in these patients remains challenging. This manuscript explores the clinical characteristics of bone fragility in adults with diabetes and highlights recent studies that have evaluated areal bone mineral density (BMD), bone microstructure and material properties, biochemical markers, and fracture prediction algorithms (FRAX) in these patients. It further reviews the impact of diabetes drugs on bone tissue as well as the efficacy of osteoporosis treatments in this population. An algorithm for the identification and management of diabetic patients at increased fracture risk is proposed.
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