• Zhongguo Zhong Yao Za Zhi · Mar 2007

    Comparative Study

    [Comparison of properties of Mahuang decoction and Maxing Shigan decoction based on biothermodynamics].

    • Dong-Li Fan, Qing-Wen Liao, Dan Yan, Xiao-Jun Ma, Xiao-He Xiao, and Yan-Ling Zhao.
    • Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China. pharmacy302@sohu.com
    • Zhongguo Zhong Yao Za Zhi. 2007 Mar 1; 32 (5): 421-4.

    ObjectiveTo probe into the objectivity and authenticity of four properties beteen Mahuang decoction and Maxing Shigan decoction from biothermodynamics.MethodThe power-time curves of growth of Staphylococcus aureus at different concentrations between Mahuang decoction and Maxing Shigan decoction were determined by TAM Air Isothermal Calorimeter. The growth rate constants of promotive and inhibitory actions were calculated. Moreover, the difference of properties beteen Mahuang decoction and Maxing Shigan decoction was analyzed from the point of view of TCM theory.ResultBoth the Mahuang decoction and Maxing Shigan decoction could inhibit the growth and metabolism of Staphylococcus aureus. The k and Pm were decreased with the mass increase of the decoction. However, inhibitory activity of Mahuang decoction with warm property was weaker than that of Maxing Shigan decoction with cool property. Moreover, Mahuang decoction decreased heat output in growth metabolism more weakly than Maxing Shigan decoction. There was a stable difference between them.ConclusionStudying on biothermodynamics can show the difference of four properties of Traditional Chinese Medicine. So, it provides a new and useful means for the study of the properties of traditional Chinese medicine.

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