• Dtsch. Med. Wochenschr. · Jul 2018

    Review

    [Peripheral neuropathy as a side effect of chemotherapy and targeted therapy].

    • Clemens Gießen-Jung and Louisa von Baumgarten.
    • Dtsch. Med. Wochenschr. 2018 Jul 1; 113 (13): 970-978.

    AbstractChemotherapy-induced peripheral neuropathy (CIPN) is a severe and common side effect induced by a variety of anticancer drugs. CIPN presents as a sensory, motor, and sometimes autonomic dysfunction with a large variability, from a mild tingling sensation and hyperesthesia, to severe neuropathic pain. Up to 40 % of patients will develop CIPN which may lead to dose-reduction or discontinuation of their current treatment and largely affects their quality of life (QoL). This review presents specific clinical features and pathomechanisms and discusses current preventive strategies and therapeutic options.© Georg Thieme Verlag KG Stuttgart · New York.

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