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Antimicrob. Agents Chemother. · Sep 2018
Randomized Controlled TrialMolecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization.
- Toney T Poovelikunnel, Paulo E Budri, Anna C Shore, David C Coleman, Hilary Humphreys, and Deirdre Fitzgerald-Hughes.
- Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland toneythomas@beaumont.ie.
- Antimicrob. Agents Chemother. 2018 Sep 1; 62 (9).
AbstractSequential methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients following attempted mupirocin nasal decolonization showed an increase in mupirocin resistance (MR) from 6.6% to 20%. MR isolates from patients who failed decolonization yielded indistinguishable spa types and carried multiple antimicrobial and antiseptic resistance genes, which may guide infection control and prevention.Copyright © 2018 American Society for Microbiology.
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