• Zhi-Fei Wang and Yan-Ming Xie.
• Institute of Basic Research in Clinical Medcine, China Academy of Chinese Medical Sciences, Beijing 100700, China. wzhftcm@163.com
• Zhongguo Zhong Yao Za Zhi. 2012 Sep 1; 37 (18): 2792-5.

ObjectiveTo explore the influencing factors of adverse event of Xiyanping injection.MethodBy use of literature metrology, we tried to collect the adverse event cases from literature, and we also obtained the sales data and HIS data of Xiyanping injection, then we made an analysis to the gender, age, allergy, disease, administration method, dosage, combined medication, solvent, time of the adverse event occur.ResultThe rate of adverse event for female was larger than male. 81.81% adverse events occurred while the treatment of respiratory infection and fever, 1/3 cases combined vitamin C injection, 89.29% cases occurred in 30 min after the transfusion begin, all of the 2 death cases have had drug allergies.ConclusionThe continue studies should be developed to find whether there is relationship between the adverse event and vitamin C injection, Doctors should pay attention to the patient after the transfusion begin in 30 min, the treatment with Xiyanping to patients who have drug allergies should be banned.

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