• J Clin Neurosci · Jun 2018

    Case Reports

    Ovarian hyperstimulation syndrome leading to ventriculoperitoneal shunt malfunction: Case report.

    • Amit Azriel, Benjamin Fleming, Uri P Dior, Samuel Moscovici, Yuval Sufaro, Mohammed Awad, and Kate Drummond.
    • Department of Neurosurgery, The Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Surgery, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: amit.azriel@mh.org.au.
    • J Clin Neurosci. 2018 Jun 1; 52: 139-140.

    AbstractVentriculoperitoneal shunt (VPS) insertion is a common neurosurgical procedure for hydrocephalus. Unfortunately, VPS malfunction is not uncommon, with an estimated cumulative rate of 32% at 5 years. As flow through the shunt is influenced by the pressure gradient between the ventricles and the peritoneal cavity, malfunction may be caused by elevated intra-abdominal pressure. We present a rare patient with ascites following ovarian hyperstimulation syndrome (OHSS) leading to shunt malfunction. OHSS is a potentially life-threatening complication of controlled ovarian stimulation caused by the administration of exogenous gonadotropins. In this patient clinical and radiological resolution of shunt dysfunction were achieved following peritoneocentesis. To our knowledge this is the first described case of OHSS leading to shunt malfunction, emphasizing the importance of awareness, early recognition and proper management of abdominal etiologies of VPS malfunction.Copyright © 2018 Elsevier Ltd. All rights reserved.

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