• Lian-Xin Wang and Yan-Ming Xie.
• Institute of Basic Research in Clinical Medcine, China Academy of Chinese Medical Sciences, Beijing 100700, China. wanglianxin_tcm@126.com
• Zhongguo Zhong Yao Za Zhi. 2012 Sep 1; 37 (18): 2804-6.

ObjectiveTo analyze the literature about clinical efficacy of Shenmai injection for tumor treatment, and understand preliminarily the medicine law and effect of Shenmai injection.MethodThe included and excluded rules are built, and the literatures about cancer treatment by "Deng feng" Shenmai injection are classified by the rules. Many kinds of information are analyzed such as published years, research types, sample size, sex and age of test-takers, dosage and evaluated parameters.ResultThe 54 literatures are brought into analysis. The small scale research below 100 people is the main type and lung cancer is the most. The evaluated parameters in these literatures include KPS improvement rate, reduction of toxicity reaction, improvement of total efective rate, improvement of clinical symptoms, improvement of one year survial rate, NK activity, LAK activity, TH/TS value and so on.ConclusionThe application of Shenmai injection for tumor treatment is increasingly extensive and some effect is got. But the quality of literature about clinical efficacy is not enough good and it cannot be adopted as evidence. It can support post-marketing reevaluation and improve the research combined with prospective experiment.

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