• Zhongguo Zhong Yao Za Zhi · Sep 2012

    Meta Analysis

    [Literature metrology analysis of adverse reactions reports of Denzhanxixin injection].

    • Yuan-Yuan Li and Yan-Ming Xie.
    • Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. chibjyy@163.com
    • Zhongguo Zhong Yao Za Zhi. 2012 Sep 1; 37 (18): 2789-91.

    ObjectiveTo investigate the effect of Dengzhanxixin injection induced adverse reactions of the general rule and characteristic, guide clinical rational drug use.MethodThrough the retrieval of 1979-2012 reported in domestic medical journals of Dengzhanxixin injection induced adverse reactions and case, literature metrology analysis analysis.ResultThe search to Dengzhanxixin injection in 25 cases of adverse drug reactions, the adverse reactions closely related with gender, age, solvent, dose, the combination drugs. The main clinical manifestations of allergic reactions, severe cases can cause allergic shock and multiple organ dysfunction.ConclusionClinicians and pharmacists should understand of Dengzhanxixin injection pattern and characteristics of adverse reactions, rational drug use norms, strengthen the application of monitoring, reduce the occurrence of adverse reactions.

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