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- Tugba Songul Tat and Aykut Cilli.
- a Department of Internal Medicine, School of Medicine , Akdeniz University , Antalya , Turkey.
- J Asthma. 2016 Dec 1; 53 (10): 1048-50.
IntroductionAsthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) is a poorly understood disease with an increasing morbidity and mortality. Currently, the most effective treatment for ACOS is unknown and omalizumab for ACOS has not yet been reported.MethodsWe report our experience with anti-IgE, omalizumab treatment on 3 patients with ACOS as a retrospective case study.ResultsAfter 1 year of omalizumab treatment, patients experienced significantly lower rates of asthma exacerbation and hospitalization and better asthma control test results.ConclusionOur study shows that omalizumab may be an effective and safe therapy for patients with ACOS. However larger randomized trials are needed.
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