• Shigui Yang, Yu Chen, Dawei Cui, Hangping Yao, Jianzhou Lou, Zhaoxia Huo, Guoliang Xie, Fei Yu, Shufa Zheng, Yida Yang, Yixin Zhu, Xiaoqing Lu, Xiaoli Liu, Siu-Ying Lau, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Kwok-Yung Yuen, Honglin Chen, and Lanjuan Li.
• State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University.
• J. Infect. Dis. 2014 Jan 15; 209 (2): 265-9.

AbstractSerological surveillance conducted in areas of an outbreak of influenza A(H7N9) infection in China found no seropositivity for antibodies specific for avian-origin influenza A(H7N9) among 1129 individuals of the general population, whereas >6% of 396 poultry workers were positive (on the basis of a hemagglutination inhibition titer of ≥ 80) for this subtype, confirming that infected poultry is the principal source of human infections and that subclinical infections are possible. Fourteen days after symptom onset, elevated levels of antibodies to A(H7N9) were found in 65.8% of patients (25/38) who survived but in only 28.6% of those (2/7) who died, suggesting that the presence of antibodies may improve clinical outcome in infected patients.

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