• Am. J. Med. · Nov 2021

    Review

    Syndrome of Non-Obstructive Coronary Artery Diseases: A Comprehensive Overview of Open Artery Ischemia.

    • Lina Ya'qoub, Islam Y Elgendy, and Carl J Pepine.
    • Department of Cardiology, Ochsner-Louisiana State University, Shreveport, La.
    • Am. J. Med. 2021 Nov 1; 134 (11): 132113291321-1329.

    AbstractSyndromes of cardiac ischemia with nonobstructive coronary arteries have been increasingly recognized as a clinical entity with heterogeneous clinical presentations, commonly encountered in women. Knowledge of pathophysiology and clinical risk factors is key to ensuring appropriate diagnostic evaluation and management for these often-neglected patients. In this review, we discuss the epidemiology, risk factors, and clinical presentations of these syndromes. We provide algorithms for diagnosis and management of these entities based on current scientific knowledge and highlight some of the key knowledge gaps and ongoing trials in this emerging field.Copyright © 2021 Elsevier Inc. All rights reserved.

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