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- Aija Knuuttila, Annamari Rouhos, Eeva-Maija Karjalainen, Henrik Riska, Matti Pietiläinen, Niina Paunu, and Eija-Riitta Salomaa.
- Helsingin yliopisto, ja HYKS:n keuhkosairauksien klinikka, PL 340, 00029 HUS.
- Duodecim. 2009 Jan 1; 125 (4): 361-8.
AbstractTreatment of advanced or metastatic non-small cell lung cancer with current cytotoxic agents is at its best able to only slow down the progression of the disease, while no curative treatment is known. Novel antiangiogenetic agents such as Bevacizumab have been expected to bring about a change in the treatment and prognosis of this disease. Two randomized studies have been conducted with Bevacizumab, whereby it was observed to make the therapeutic results more effective when combined with a cytotoxic platinum agent in a selected patient group. In our opinion the current scientific evidence does not yet support the use of Bevacizumab as the standard therapy for lung cancer.
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