• S. Afr. Med. J. · Apr 2021

    Practice Guideline

    Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia.

    • B F Jacobson, E Schapkaitz, M Mer, S Louw, S Haas, H R Buller, B Brenner, A T O Abdool-Carrim, P De Jong, P Hsu, D Jankelow, M Lebos, B Levy, H Radford, P Rowji, L Redman, M Sussman, D Van der Jagt, P F Wessels, P G Williams, and On Behalf Of The Southern African Society Of Thrombosis And Haemostasis.
    • Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. elise.schapkaitz@nhls.ac.za.
    • S. Afr. Med. J. 2021 Apr 20; 111 (6): 535-537.

    AbstractThere have recently been safety concerns regarding an increased risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) following administration of SARS-CoV-2 adenoviral vector vaccines. The Southern African Society of Thrombosis and Haemostasis reviewed the emerging literature on this idiosyncratic complication. A draft document was produced and revised by consensus agreement by a panel of professionals from various specialties. The recommendations were adjudicated by independent international experts to avoid local bias. We present concise, practical guidelines for the clinical management of VITT.

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