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Pneumonol Alergol Pol · Jan 2014
Methodological recommendations for the diagnostics of EGFR gene mutations and ALK gene rearrangement in the selection of non-small-cell lung cancer patients to molecularly targeted therapies.
- Paweł Krawczyk, Joanna Chorostowska-Wynimko, Rafał Dziadziuszko, Jacek Jassem, Maciej Krzakowski, Renata Langfort, Elżbieta Puacz, Bartosz Wasąg, and Kamila Wojas-Krawczyk.
- Pracownia Immunologii i Genetyki Katedry i Kliniki P neumonologii, Onkologii i Alergologii Uniwersytetu Medycznego w Lublinie. krapa@poczta.onet.pl.
- Pneumonol Alergol Pol. 2014 Jan 1; 82 (5): 437-44.
AbstractTesting for EGFR gene mutations and ALK gene rearrangement is routinely used in advanced non-small-cell lung cancer for adequate patient selection to molecularly targeted therapies. We present Polish methodological recommendations for molecular analysis of EGFR and ALK genetic abnormalities. Recommendations specify clinical indications for testing, sample types and handling, as well as requirements for laboratories performing molecular diagnostics.
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