• Mansoor Zafar, Mangala Karkhanis, Muhammad Shahbaz, Alisha Khanna, Lucinda Barry, Saba Alam, Kamal Lawrence, Bipin Pun, Reem Eldebri, Opeyemi Makanjuola, Dana Safarova, Mariya Farooq, Hesam Nooredinavand, Frderic Cuison, Karuna Subba, Ratan Singh Randhawa, Johannes Hegner, Ojofeitimi Oluwamayowa, Amr Elyasaky, Bolurin Adekunle, Manivannan Periasamy, Mohamed Abdelbagi, Zahra Maryam, Bao Khuu, Andreia Esteves Morete, Giulio Ciroi, Steve Moran, William O'Neill, Maaryah J Zafar, Nadiyah Zafar, Mirej Patel, Raphael Golez, Abubakr Hadid, Tila Muhammad, Philip Mayhead, Mark Whitehead, and Umesh Dashora.
• Gastroenterology, GIM, Conquest Hospital, Saint Leonards on Sea, UK 1mansoorzafar@gmail.com.
• Postgrad Med J. 2022 Jul 1; 98 (1161): 523528523-528.

BackgroundThe role of vitamin D in increased mortality with SARS-COV-2 virus, namely, COVID-19, remains uncertain. We analysed all the patients who were treated as COVID-19-positive with or without a positive swab and were tested for vitamin D levels.MethodsThis was a retrospective, study involving 1226 patients swabbed for SARS-CoV-2 between the 10 February 2020 and 1 May 2020 at two hospitals of East Sussex Healthcare NHS Trust. Patients who were swab-positive for COVID-19 or treated as COVID-19-positive on clinical grounds even though swab results were negative were included in this study. We analysed the association of vitamin D levels and mortality, assessing linear and non-linear associations.ResultsA total of 1226 patients had SARS-CoV-2 RNA swabs in this period with age range from 1 year to 101 years. A cohort of 433 of these patients had swabs and recent vitamin D levels anytime in the previous 3 months. Mortality rates were not found to be associated with vitamin D levels (OR=1.04, 95% CI 0.96 to 1.12).ConclusionOur findings suggest similar mortality risk from COVID-19 irrespective of the levels of vitamin D. Larger prospective studies will be needed to confirm these findings.© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

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