• Critical care clinics · Oct 2021

    Review

    Acute Respiratory Distress Syndrome: Ventilator Management and Rescue Therapies.

    • Melissa H Coleman and J Matthew Aldrich.
    • Division of Cardiothoracic Surgery, Department of Surgery, Critical Care Medicine, University of California, San Francisco, 500 Parnassus Avenue, MUW-405, Box 0118, San Francisco, CA 94143, USA.
    • Crit Care Clin. 2021 Oct 1; 37 (4): 851866851-866.

    AbstractThis review describes the management of mechanical ventilation in patients with acute respiratory distress syndrome, including in those with coronavirus disease 2019. Low tidal volume ventilation with a moderate to high positive end-expiratory pressure remains the foundation of an evidence-based approach. We consider strategies for setting positive end-expiratory pressure levels, the use of recruitment maneuvers, and the potential role of driving pressure. Rescue therapies including prone positioning and extracorporeal membrane oxygenation are also discussed.Copyright © 2021 Elsevier Inc. All rights reserved.

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