• Critical care clinics · Oct 2021

    Review

    Pharmacologic Treatments for Acute Respiratory Distress Syndrome.

    • Nida Qadir and Steven Y Chang.
    • David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Room 43-229 CHS, Los Angeles, CA 90095, USA. Electronic address: nqadir@mednet.ucla.edu.
    • Crit Care Clin. 2021 Oct 1; 37 (4): 877893877-893.

    AbstractAcute respiratory distress syndrome is a heterogenous syndrome with many etiologies for which there are no definitive pharmacologic treatments, despite decades of research. We explore some adjunctive pharmacologic therapies, including neuromuscular blockade, corticosteroids, and inhaled pulmonary vasodilators. Additionally, we explore some investigative therapies, including Vitamin C, beta-agonists, statins, mesenchymal stromal cells, and granulocyte-macrophage colony stimulating factor. We do discuss the potential role of steroids in acute respiratory distress syndrome with severe acute respiratory syndrome coronavirus 2 as a trigger. The standard of care, however, remains supportive care.Copyright © 2021 Elsevier Inc. All rights reserved.

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