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- Jack D Sobel.
- Department of Medicine, Wayne State University School of Medicine, Detroit, MI, USA. jsobel@med.wayne.edu
- Lancet. 2007 Jun 9; 369 (9577): 1961-71.
AbstractDespite therapeutic advances, vulvovaginal candidosis remains a common problem worldwide, affecting all strata of society. Understanding of anti-candida host defence mechanisms in the vagina has developed slowly and, despite a growing list of recognised risk factors, a fundamental grasp of pathogenic mechanisms continues to elude us. The absence of rapid, simple, and inexpensive diagnostic tests continues to result in both overdiagnosis and underdiagnosis of vulvovaginal candidosis. I review the epidemiology and pathogenesis of this infection, and also discuss management strategies.
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