• J Res Med Sci · Jul 2013

    Case Reports

    A significant response to sunitinib in a patient with anaplastic thyroid carcinoma.

    • Enrique Grande, Jaume Capdevila, Juan José Díez, Federico Longo, and Alfredo Carrato.
    • Department of Medical Oncology, Ramón Y Cajal University Hospital, Madrid, Spain.
    • J Res Med Sci. 2013 Jul 1; 18 (7): 623-5.

    AbstractAnaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been considered standard for the last decades. Novel multitarget agents have shown promising responses; however, no positive randomized clinical trials are available up to now. To our knowledge, the case we are presenting here is the first reported case showing clinical and visual activity using sunitinib as a salvage treatment in an ATC patient who was not fit to receive systemic chemotherapy treatment.

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