• Der Unfallchirurg · Dec 2008

    Case Reports

    [Postoperative manifestation of acute compartment syndrome by previously unknown heterozygote sickle cell anemia. A clinical case report].

    • A Schulz, A C Disch, I Melcher, N P Haas, and K-D Schaser.
    • Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland. antje.schulz@charite.de
    • Unfallchirurg. 2008 Dec 1; 111 (12): 1021-4.

    AbstractPatients suffering from sickle cell disease show an increased ischemic intolerance due to continuous pro-inflammatory activation and dysfunction of the endothelium by recurrent vaso-occlusive episodes. The presented case shows the manifestation of a postoperative compartment syndrome of the lower leg following the intraoperative use of blood arrest in a patient with previously unknown sickle cell disease. Preexisting vulnerability for tissue hypoxia in patients at risk should be a major concern for intraoperative use of blood arrest during surgery of the extremities.

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