• R Hierner, G Täger, and D Nast-Kolb.
• Plastische, Rekonstruktive, Asthetishe und Handchirurgie, Zentrum für Interdisziplinäre Rekonstruktive Chirurgie, Universitätsklinikum Essen der Universität Duisburg-Essen, Hufelandstrasse 55, Essen, Germany. robert.hierner@uk-essen.de
• Unfallchirurg. 2009 Apr 1; 112 (4): 405-16; quiz 417-8.

AbstractVascularized pedicled bone grafts are known since the beginning of the last century. Microvascular bone grafts (free vascularized bone transfer) are known since the beginning of the seventies. In many experimental and clinical studies vascularized bone grafts were compared to their non-vascularized analogues. Because of their own non-interrupted blood supply and thus nearly normal vitality vascularized bone grafts show more rapid fracture healing, more pronounced adaptation to the new mechanical loadings (e. g. graft hypertrophy), higher survival and consolidation rate in poor or bad recipient bed conditions (infection, bad vascularization) and some neovascularization potential on the surrounding tissue. Because of those properties, it became possible to successfully treat a large segmental bone defect by only few operations. As the treatment of complicated combined soft tissue/bone defects led to high complication rate up to 40 to 60% the indications of this method were altered.

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