• Hongdong Tan, Jia Gu, Liang Xu, and Gang Sun.
• Department of Orthopedics, Shandong public Health Clinical Center (Shandong Province Chest Hospital), Shandong Province, P.R. China.
• Medicine (Baltimore). 2021 Sep 17; 100 (37): e27288.

RationaleSolitary bone plasmacytoma (SBP) is a rare manifestation of plasma cell tumor. Although axial skeleton is the most frequently affected site of SBP, adjacent disc space involvement is rare. Herein we report a case of SBP in thoracic vertebra with involvement of adjacent disc space.Patient ConcernsA 57-year-old male presented with a 2-year history of intermittent back pain with activity. The patient's back pain intensity with activity was a score of 5 of the 10-point visual analog scale).Diagnoses And InterventionThe patient underwent a posterior fusion procedure from T6 to T10, and an open biopsy of the vertebral lesion confirmed that final diagnosis of SBP. The patient received postoperative radiotherapy with a total of 4000 Gy to the T7-T9 vertebral levels over a 20-day period.OutcomesFollowing radiotherapy, the patient's pain intensity was reduced to the visual analog scale score of 1 at the 6-month follow-up.LessonsSBP lacks typical clinical symptoms, and the accurate diagnosis before clinical intervention remains challenging. Due to the disc involvement, SBP often manifests as spinal infection. Hence, differential diagnosis in spinal lesions involving the disc should include SBP.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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