• Korhan Soylu, Okan Gulel, Huriye Yucel, Serkan Yuksel, Gokhan Aksan, Ayşegül İdil Soylu, Sabri Demircan, Ozcan Yılmaz, and Mahmut Sahin.
• Korhan Soylu, MD, Assistant Professor, Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
• Pak J Med Sci. 2014 Sep 1; 30 (5): 936-41.

Background And ObjectiveThe coronary slow flow phenomenon (CSFP) is a coronary artery disease with a benign course, but its pathological mechanisms are not yet fully understood.The purpose of this controlled study was to investigate the cellular content of blood in patients diagnosed with CSFP and the relationship of this with coronary flow rates.MethodsSelective coronary angiographies of 3368 patients were analyzed to assess Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) values. Seventy eight of them had CSFP, and their demographic and laboratory findings were compared with 61 patients with normal coronary flow.ResultsPatients' demographic characteristics were similar in both groups. Mean corrected TFC (cTFC) values were significantly elevated in CSFP patients (p<0.001). Furthermore, hematocrit and hemoglobin values, and eosinophil and basophil counts of the CSFP patients were significantly elevated compared to the values obtained in the control group (p=0.005, p=0.047, p=0.001 and p=0.002, respectively). The increase observed in hematocrit and eosinophil levels showed significant correlations with increased TFC values (r=0.288 and r=0.217, respectively).ConclusionSignificant changes have been observed in the cellular composition of blood in patients diagnosed with CSFP as compared to the patients with normal coronary blood flow. The increases in hematocrit levels and in the eosinophil and basophil counts may have direct or indirect effects on the rate of coronary blood flow.

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