• Medicina · Oct 2021

    Review

    Bullous Pemphigoid and Other Pemphigoid Dermatoses.

    • Valeryia Pratasava, Vikram N Sahni, Aishwarya Suresh, Simo Huang, Abhirup Are, Sylvia Hsu, and Kiran Motaparthi.
    • College of Medicine, Drexel University, Philadelphia, PA 19129, USA.
    • Medicina (Kaunas). 2021 Oct 4; 57 (10).

    AbstractThe pemphigoid family of dermatoses is characterized by autoimmune subepidermal blistering. The classic paradigm for pemphigoid, and the most common member, is bullous pemphigoid. Its variable clinical presentation, with or without frank bullae, is linked by significant pruritus afflicting the elderly. Mucous membrane pemphigoid is an umbrella term for a group of subepidermal blistering dermatoses that favor the mucosal membranes and can scar. Epidermolysis bullosa acquisita is a chronic blistering disorder characterized by skin fragility, sensitivity to trauma, and its treatment-refractory nature. Clinicians that encounter these pemphigoid disorders may benefit from an overview of their clinical presentation, diagnostic work-up, and therapeutic management, with an emphasis on the most frequently encountered pemphigoid disease, bullous pemphigoid.

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