• Wien. Klin. Wochenschr. · Sep 2018

    Ruxolitinib therapy for myelofibrosis in Austria : Consensus on therapy management.

    • Maria-Theresa Krauth, Sonja Burgstaller, Veronika Buxhofer-Ausch, Günther Gastl, Klaus Geissler, Felix Keil, Peter Krippl, Thomas Melchardt, Andreas Petzer, Holger Rumpold, Thamer Sliwa, Stefan Wöhrer, Albert Wölfler, and Heinz Gisslinger.
    • Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, Austria. maria.krauth@meduniwien.ac.at.
    • Wien. Klin. Wochenschr. 2018 Sep 1; 130 (17-18): 495-504.

    AbstractThe oral Janus associated kinase (JAK1/2) inhibitor ruxolitinib has been available for treatment of patients with intermediate or high-risk myelofibrosis in Europe since 2012. Since its introduction, the expertise of prescribing doctors with respect to ruxolitinib function, efficacy and adverse effects has consistently been augmented, resulting in therapy modalities that are better tailored to individual patients as well as in increased safety of the treatment. The present consensus on ruxolitinib therapy management has been elaborated by Austrian experts in myeloproliferative neoplasms in line with international treatment guidelines. Our recommendations aim to contribute to an improved management of patients with myelofibrosis treated with ruxolitinib.

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