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- B A Racette, G Lopate, L Good, S Sagitto, and J S Perlmutter.
- Department of Neurology and Neurological Surgery, Washington University Sxhool of Medicine, St. Louis, MO 63110, USA. racetteb@neuro.wustl.edu
- Neurology. 2002 Nov 12; 59 (9): 1445-7.
AbstractThe authors report a patient with cervical dystonia, previously treated with botulinum toxin A (BTX-A), who developed bilateral ptosis and difficulty with accommodation only after botulinum toxin B (BTX-B). High-frequency repetitive nerve stimulation of the abductor digiti minimi demonstrated a 34% increment in compound muscle action potential. No increment in 20 people injected with BTX-A and no cases of ptosis in a chart review of 1,606 BTX-A injections for cervical dystonia were found. The authors conclude that systemic spread of BTX-B can cause symptomatic involvement of autonomic neurons.
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