• Emerg. Med. Clin. North Am. · Feb 2022

    Review

    Mimics of Allergy and Angioedema: Scombroid, Mast Cell Activation Disorders, and Hereditary Alpha Tryptasemia.

    • Elizabeth G Thomas and Daniel James Thomas.
    • Department of Emergency Medicine, Ochsner Medical Center, 1514 Jefferson Highway, Jefferson, New Orleans, LA 70121, USA. Electronic address: elizabeth.thomas@ochsner.org.
    • Emerg. Med. Clin. North Am. 2022 Feb 1; 40 (1): 119-133.

    AbstractScombroid poisoning, systemic mastocytosis, and hereditary alpha tryptasemia all present with episodes that resemble allergic reactions. Knowledge regarding systemic mastocytosis and hereditary alpha tryptasemia is quickly evolving. Epidemiology, pathophysiology, and strategies to identify and diagnose are discussed. Evidence-based management in the emergency setting and beyond is also explored and summarized. Key differences are described between these events and allergic reactions.Copyright © 2021 Elsevier Inc. All rights reserved.

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