• Farzan Dholoo, Amanda Shabana, Myrella Paschali, MandalAmit K JAKJWexham Park Hospital, Frimley Health NHS Foundation Trust, Internal Medicine, Berkshire, UK. Electronic address: amit.mandal@nhs.net., and Constantinos G Missouris.
• Wexham Park Hospital, Frimley Health NHS Foundation Trust, Internal Medicine, Berkshire, UK. Electronic address: farzan.dholoo@nhs.net.
• J Clin Neurosci. 2020 Feb 1; 72: 458-460.

AbstractTolosa-Hunt syndrome is a rare disorder characterized by severe peri-orbital headache and ophthalmoplegia resulting from pseudotumour in the cavernous sinus compressing structures within it, namely cranial nerves III, IV, and VI and the superior divisions of cranial nerve V. We report the case of a 47 year old female who presented with painless left unilateral ptosis and complete external ophthalmoplegia. Magnetic Resonance Imaging (MRI) identified an enhancing heterogeneous mass filling the left cavernous sinus, following the course of the oculomotor nerve. After 2 weeks symptoms and signs resolved and there was a parallel resolution of the MRI findings, without the administration of corticosteroids. As far as we are aware this is one of the first reports of Tolosa-Hunt syndrome variant, with painless neurological involvement confined solely to the oculomotor nerve, and with complete resolution without pharmacological intervention.Copyright © 2019 Elsevier Ltd. All rights reserved.

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