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Case Reports
Treatment of tuberculous meningitis in adults: Is the duration of intensive-phase therapy adequate?
- S Moodley, M S Dlwati, and A I Bhigjee.
- Department of Neurology, Inkosi Albert Luthuli Central Hospital, Durban, South Africa. sharmoodley@gmail.com.
- S. Afr. Med. J. 2021 Apr 30; 111 (5): 412-415.
AbstractTuberculous meningitis (TBM) results in considerable morbidity and mortality, especially in developing countries such as South Africa. Treatment regimens have been extrapolated from treatment for pulmonary tuberculosis, and the intensive-phase duration of 2 months may be inadequate for treatment of patients with TBM. We highlight this situation with a case report of a patient with TBM whose illness progressed after institution of the maintenance phase of treatment. We propose that the intensive-phase treatment of TBM be revisited with regard to duration of treatment, choice of drugs during continuation-phase therapy, or both.
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