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- W C Tan, T B Chan, T K Lim, and E C Wong.
- Department of Medicine, National University Hospital, Singapore.
- Singap Med J. 1990 Apr 1; 31 (2): 142-6.
AbstractWe studied 22 Asian patients with steroid dependent asthma. Using a clinical approach to the addition of high dose inhaled budesonide and tapering of systematic steroid, we were able to substitute 5 to 20 mg prednisolone with 800 micrograms per day of inhaled budesonide in all patients. There was also a greater reduction in nocturnal symptoms and awakenings and a smaller overnight fall in PEFR during treatment with budesonide than with prednisolone. Inhaled budesonide was an effective long term substitute for prednisolone in chronic asthma.
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