• The Journal of pediatrics · Jun 2016

    Randomized Controlled Trial Multicenter Study

    High-Sensitivity Troponin T and N-Terminal Pro-Brain Natriuretic Peptide in Prediction of Outcome in Congenital Diaphragmatic Hernia: Results from a Multicenter, Randomized Controlled Trial.

    • Kitty G Snoek, Ulrike S Kraemer, Chantal A Ten Kate, Anne Greenough, Arno van Heijst, Irma Capolupo, Thomas Schaible, Joost van Rosmalen, René M Wijnen, Irwin K M Reiss, and Dick Tibboel.
    • Intensive Care and Department of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
    • J. Pediatr. 2016 Jun 1; 173: 245-249.e4.

    UnlabelledBiomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia.Trial RegistrationNetherlands Trial Registry: 1310.Copyright © 2016 Elsevier Inc. All rights reserved.

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