• J Trauma Nurs · Jan 2013

    Comparative Study

    Morphine versus fentanyl for pain due to traumatic injury in the emergency department.

    • Bradley R Wenderoth, Elizabeth T Kaneda, Albert Amini, Richard Amini, and Asad E Patanwala.
    • Department of Pharmacy, University of Southern California School of Pharmacy, Los Angeles, USA.
    • J Trauma Nurs. 2013 Jan 1;20(1):10-5.

    AbstractThe analgesic response and safety of intravenous morphine versus fentanyl for adult trauma patients who presented to the emergency department (ED) were evaluated. Median pain reduction on the numeric rating scale (0-10; 0 = no pain and 10 = worst possible pain) after opioid administration was similar between the groups (2 vs 2; P = .67). The lowest postdose pain score was recorded sooner in the fentanyl group than in the morphine group (22 vs 47 minutes, respectively; P < .001). There were no significant differences in drug-induced adverse effects between groups. Fentanyl produced a similar but more rapid analgesic response compared with morphine in trauma patients.

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