• Nian-Ge Xia, Yan-Yan Chen, Xin-Shi Wang, Hui-Qin Xu, and Rong-Yuan Zheng.
• Department of Neurology, the First Affiliate Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang, P.R. China.
• Medicine (Baltimore). 2017 Nov 1; 96 (45): e8508.

RationaleGarcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs.Patient ConcernsWe report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years.DiagnosisA left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis.InterventionsThe patient was treated 3 times with local-field palliative radiotherapy.OutcomesShe died after several months.LessonsTo the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome.

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