• Dusko Ilic, Ljiljana Vicovac, Milos Nikolic, and Emilija Lazic Ilic.
• Stem Cell Laboratories, Guy's Assisted Conception Unit, Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK dusko.ilic@kcl.ac.uk.
• Br. Med. Bull. 2016 Mar 1; 117 (1): 59-67.

BackgroundHuman amniotic membrane (HAM) has been embraced as a natural wound dressing almost exclusively in ophthalmology. Only recently, emergence of commercial HAM products prompted its use in growing range of indications, especially treatment of chronic non-healing wounds.Sources Of DataClinicalTrials.gov database and International Clinical Trials Registry Platform searched with key words 'human amniotic membrane' and 'chronic wounds'.Areas Of AgreementHAM can be successfully used as a natural wound dressing to promote healing.Areas Of ControversyIt is still unclear, which preparation is more advantageous, cryopreserved HAM or dehydrated HAM.Growing PointsThere are an increasing number of commercial HAM products and clinical trials for a variety of dermatological diagnoses.Areas Timely For Developing ResearchIn spite of easy procurement and low production costs, to our knowledge, there are currently only a few manufacturers of commercial HAM products tested in clinical trials for cutaneous wounds and all of them are located in the USA.© The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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