• Heun Choi, KimMoo HyunMHhttps://orcid.org/0000-0003-3634-0296Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea., Se Ju Lee, Eun Jin Kim, Woonji Lee, Wooyong Jeong, In Young Jung, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Ji Hyeon Baek, Young Hwa Choi, Hyo Youl Kim, June Myung Kim, and Jun Yong Choi.
• Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
• J. Korean Med. Sci. 2018 Nov 19; 33 (47): e296.

BackgroundAntepartum, intrapartum, and postpartum preventive measures with antiretroviral drugs, appropriate delivery methods, and discouraging breastfeeding significantly decrease the risk of mother-to-child transmission of human immunodeficiency virus (HIV) infection. Herein, we investigated the pregnancy outcomes in HIV-infected Korean women.MethodsWe retrospectively reviewed medical records of childbearing-age HIV-infected women between January 2005 and June 2017 at four tertiary care hospitals in Korea.ResultsAmong a total of 95 HIV infected women of child-bearing age with 587.61 years of follow-up duration, 15 HIV-infected women experienced 21 pregnancies and delivered 16 infants. The pregnancy rate was 3.57 per 100 patient-years. Among the 21 pregnancies, five ended with an induced abortion, and 16 with childbirth including two preterm deliveries at 24 and 35 weeks of gestation, respectively. The two preterm infants had low birth weight and one of them died 10 days after delivery due to respiratory failure. Among the 14 full-term infants, one infant was small for gestational age. There were no HIV-infected infants.ConclusionThe pregnancy rate of HIV-infected women in Korea is lower than that of the general population. Although several adverse pregnancy outcomes were observed, mother-to-child transmission of HIV infection was successfully prevented with effective preventive measures.

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