• Emerg. Med. Clin. North Am. · May 1994

    Review

    Beta-blocker and calcium channel blocker toxicity.

    • W Kerns, J Kline, and M D Ford.
    • Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina.
    • Emerg. Med. Clin. North Am. 1994 May 1; 12 (2): 365-90.

    AbstractToxicity from beta-blocker and calcium channel blocker drugs is a challenging medical emergency with steadily increasing incidence. Clinical manifestations of intoxication with these drugs are presented in light of known pharmacologic and pharmacokinetic properties, as well as the physiology of the beta-adrenoreceptor and calcium channel. Review of clinical and basic science literature provides the basis for specific management guidelines for beta-blocker and calcium channel blocker toxicity.

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