• R Conway, S Cournane, D Byrne, D O'Riordan, and B Silke.
• Department of Internal Medicine, St. James's Hospital, Dublin, 8, Ireland.
• Ir J Med Sci. 2018 Feb 1; 187 (1): 5-11.

BackgroundMultiple studies have suggested an association between weekend hospital admissions and mortality. These have been limited by potential residual confounders and a lack of explanation of causation.AimWe previously attributed adverse weekend outcomes to higher acuity; we have re-examined this question for all emergency medical admissions to our institution from 2002 to 2014.MethodsWe divided admissions by a weekday or weekend (Friday to Sunday) hospital arrival. We utilised a multivariate logistic regression model, to determine whether the latter was independently predictive of 30-day in-hospital mortality.ResultsThere were 82,368 admissions in 44,628 patients over the 13-year period. Of admissions, 37.4% occurred at the weekend. The Acute Illness Severity Score, the Charlson Co-morbidity Index and the Chronic Disabling Disease Score were similar by a weekday or weekend admission. The multivariable logistic regression showed no increase in 30-day in-hospital mortality for weekend admissions, odds ratio 1.07 (95% confidence interval 0.98 to 1.16) (p = 0.11). Since the inception of the AMAU, the per patient mortality for a weekend admission has declined from 13.5% in 2002 to 4.4% in 2014. This represents a relative risk reduction of 67.9% with a number needed to treat of 10.8. Outcomes improved similarly for weekday and weekend admissions.ConclusionNo increase in 30-day in-hospital mortality for weekend admissions was found in this study. There has been a substantial reduction in mortality for both weekday and weekend admissions over time.

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